Although, as I’ve proven to be the case, the transplantation of freshly extirpated genital glands into subjects of the alternative sex has no impact, it doesn’t follow that the injection of the ovarian secretion into the blood of a male may not have a most injurious effect. The inner secretions of the genital glands have to be considered finishing the sexuality of the individual. The restricted affect of the internal secretions of the sexual glands in forming the sexual characters should be realised to warrant the theory of a major, typically slight, difference in every cell, however still determinate sexual affect. Such secondary sexual characters are greatest outlined as those which begin to seem at puberty, and which can’t be developed besides underneath the influence on the system of the internal secretions of the genital glands. The relation of this affect or its absence (as within the case of artificially castrated animals) has been traced out in the diploma of improvement of the secondary characters. Examples of these are the beards in males, the luxuriant growth of hair in girls, the event of the mammary glands, the character of the voice. There are a lot of instances (too readily interpreted as cases of full assumption of the male character) by which after the involution of the female sexual glands on the climacteric the secondary sexual characters of the male are acquired.
As a matter of truth, the internal secretions of all the glands have to be thought to be affecting all the tissues. Every cell must be thought-about as possessing an unique sexuality, to which the affect of the internal secretion in sufficient amount is the ultimate figuring out situation beneath the influence of which the cell acquires its closing determinate character as male or feminine. In truth it could also be taken as certain that an approximation to a complete uniformity of sexual character over the entire body is much more frequent than the tendency to any considerable divergences amongst the completely different organs or nonetheless extra amongst the completely different cells. I might say up to now couple of years, he has become much more emotionally intimate with me. In this connection, I could say a phrase as to the curative worth of organotherapy. At current empirical data does not allow us to say whereby the masculinity or the femininity of a cell actually lies, or to define the histological, molecular or chemical variations which distinguish each cell of a male from every cell of a female.
It is usually to be desired, from the theoretical perspective, that knowledge may be gained as to whether the interior secretion of the genital glands enters into chemical union with the protoplasm of the cells or whether or not it acts as a physiological stimulus independent of the amount provided. Many phenomena, amongst which may be observed specially experiments on the regeneration of lost components and investigations into the chemical differences between the corresponding tissues of practically allied animals, have led the investigators to whom I’ve just referred to conceive the existence of an “Idioplasm,” which is the bearer of the specific characters, and which exists in all of the cells of a multi-cellular animal, quite apart from the purposes of reproduction. In an analogous vogue I have been led to the conception of an “Arrhenoplasm” (male plasm) and a “Thelyplasm” (female plasm) as the 2 modes by which the idioplasm of every bisexual organism could appear, and which are to be thought of, due to causes which I shall explain, as ultimate circumstances between which the actual conditions all the time lie.
